By Nina C. Gonnella
February 04, 2020
The isolation and structural characterization of substances present at very low concentrations, as is necessary to satisfy regulatory requirements for pharmaceutical drug degradants and impurities, can present scientific challenges. The coupling of HPLC with NMR spectroscopy has been at the ...
Edited
By Tomasz Tuzimski, Joseph Sherma
October 30, 2018
Xenobiotics are chemical compounds foreign to a given biological system. In animals and humans, xenobiotics include drugs, drug metabolites, and environmental pollutants. In the environment, xenobiotics include synthetic pesticides, herbicides, and industrial pollutants. Many techniques are used in...
Edited
By Łukasz Komsta, Yvan Vander Heyden, Joseph Sherma
February 20, 2018
Chemometrics uses advanced mathematical and statistical algorithms to provide maximum chemical information by analyzing chemical data, and obtain knowledge of chemical systems. Chemometrics significantly extends the possibilities of chromatography and with the technological advances of the personal...
Edited
By Teresa Kowalska, Mieczyslaw Sajewicz, Joseph Sherma
February 20, 2018
There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents ...
Edited
By Perry G. Wang, Weixuan He
May 22, 2017
This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid...
Edited
By Leo M.L. Nollet, Dimitra A. Lambropoulou
February 23, 2017
This detailed handbook covers different chromatographic analysis techniques and chromatographic data for compounds found in air, water, and soil, and sludge. The new edition outlines developments relevant to environmental analysis, especially when using chromatographic mass spectrometric techniques...
Edited
By Teresa Kowalska, Mieczyslaw Sajewicz, Joseph Sherma
November 24, 2015
Planar Chromatography–Mass Spectrometry focuses on a relatively new approach to chemical analysis in general, and to separation science in particular. It is the first book to systemically cover the theoretical background, techniques, instrumentation, and practical applications of planar ...
Edited
By Tomasz Tuzimski, Joseph Sherma
May 26, 2015
HPLC is the principal separation technique for identification of the pesticides in environmental samples and for quantitative analysis of analytes. At each stage of the HPLC procedure, the chromatographer should possess both the practical and theoretical skills required to perform HPLC experiments ...
Edited
By Ecaterina Stela Dragan
September 30, 2014
Advanced Separations by Specialized Sorbents opens a new window into sorbent materials, presenting fundamental principles for their syntheses and adsorption properties. The book presents advanced techniques used to create specialized sorbents with a wide range of functions that can be used to ...
Edited
By Heewon Lee
September 04, 2014
A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists in the pharmaceutical industry today. Pharmaceutical Industry Practices on Genotoxic Impurities strives to facilitate scientific and systematic consensus on GTI management by ...
Edited
By Łukasz Komsta, Monika Waksmundzka-Hajnos, Joseph Sherma
February 12, 2014
Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It requires less complicated or expensive equipment than other techniques, and has the ability to be performed under ...
Edited
By Monika Waksmundzka-Hajnos, Joseph Sherma
November 19, 2010
The powerful, efficient technique of high performance liquid chromatography (HPLC) is essential to the standardization of plant-based drugs, identification of plant material, and creation of new herbal medicines. Filling the void in this critical area, High Performance Liquid Chromatography in ...
